I was able to get a Geno 2.0 Next test from Helix on sale and use a coupon to make it fairly inexpensive. I talked (e-mail and chat) with National Geographic and Helix about their opinion on the differences between my earlier Geno 2.0 results (done when FamilyTree DNA aka FTDNA was still processing U.S. kits) before I ordered the test. Both companies were of the opinion there would be no differences, or at most minimal differences between the old FTDNA test and any new results from my Helix test. I added the Geno 2.0 Next results to Ignore Ethnic Results Below the Continental Level so you could see how Geno 2.0 Next compared to the various other companies I tested with.
While Helix examines a larger amount of DNA which they call Exome+ https://support.helix.com/hc/en-us/articles/115009675007-What-is-Exome- (link has changed), you don’t get free access to the information. You would need to pay to download it from Helix and it appears to cost almost $500 to do so.
It reads all 20,000 or so of our genes that are considered important because they code for proteins, the functional players in the body — known as the exome. The “+” means that we have added hundreds of thousands of other regions of interest, from data important to provide insights about ancestry to markers that are associated with a wide range of health conditions.
The end result is that the Exome+ provides 100 times the amount of information provided by existing genotyping or array technologies that are currently available to consumers. This is important for many reasons. With Exome+ sequencing, we can do a better job interpreting your data today, and we can find rare variations that cannot be found using arrays.
The haplogroups were the same with Geno 2.0 Next and Geno 2.0, but I wasn’t expecting any difference there.
Neanderthal for Geno 2.0 Next (Helix) 1.5%; Geno 2.0 (FTDNA) 2.5% and no Denisovan for Geno 2.0 Next.
Ethnicity differences were in my opinion, sizeable although the rearranging of several sections made it a little more interesting to try and figure out (see below for how the two tests compared in terms of ethnicity):
Geno 2.0 Next (Helix version, July 2018 and including comparison between Geno 2.0 – FTDNA with Geno 2.0 Next – Helix):
Ethnicity Results Comparison*:
Geno 2.0 Next (Helix):
Northwestern European 56%
Northeastern European 15%
Southwestern European 8%
West Mediterranean 7%
Eastern European 7%
Italy and Southern Europe 6%
Geno 2.0 (FTDNA)
Northern European 42%
Southwest Asian 16%
*Worth noting 2.0 Next added some ethnicity areas that weren’t listed in 2.0 results although Nat Geo was of the opinion changes should have been made to 2.0 results as improvements and changes were made.
Neanderthal/Denisovan Results Comparison:
Geno 2.0 Next (Helix)
Geno 2.0 (FTDNA)
Geno 2.0 Next (Helix) vs. Geno 2.0 (FTDNA)
Haplogroup Results (the same with both companies and kits):
Y-DNA J-YSC0000234 (specifically J1)